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 Russell Publishing Ltd
 Court Lodge
 Hogtrough Hill
 Brasted
 Kent TN16 1NU. UK
 Registered in England 
 No. 2709148
 Registered office as above.
 VAT No. GB 577 897847

 

Enthalpic efficiency and the role of thermodynamic data in drug development: possibility or a pipeline dream!

publication date: Nov 23, 2007
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The determination of accurate thermodynamic data for the interactions of biomolecules has been enhanced over the last decade by the use of isothermal titration calorimetric (ITC) instrumentation. These instruments are now standard kits in many biophysical/structural biochemistry laboratories of pharmaceutical companies. Despite this, there is little evidence for the input of thermodynamic data into the drug development process.



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